Place onions and sugar in a sprayed pan; cook over medium heat for about 8 to 10 minutes or until lightly browned and caramelized. Mix mustard, horseradish and honey; spread onto 2 slices bread. layer each with 3 slices ham, 2 tablespoons caramelized onions, and 1 slice Swiss cheese, top with break. Spray each side of panini with cooking spray and grill until browned.
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